Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Borneol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Borneol SCHEMBL28002051 | 0.93 | EPHX2 (0.43) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL4608836 | 0.93 | EPHX2 (0.43) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL1819627 | 0.93 | EPHX2 (0.43) | EPHX2ALDH1A1LMNA | |
| Borneol SCHEMBL1819628 | 0.93 | EPHX2 (0.43) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL700565 | 0.91 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Borneol SCHEMBL9719854 | 0.91 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL9719858 | 0.91 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL9719849 | 0.91 | EPHX2 (0.41) | EPHX2ALDH1A1LMNA | |
| Borneol SCHEMBL17144629 | 0.88 | EPHX2 (0.44) | EPHX2ALDH1A1LMNA | |
| Dexborneol SCHEMBL17144628 | 0.88 | EPHX2 (0.44) | EPHX2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110354048-A | A kind of natural plant active composition and the preparation method and application thereof | 西安优露清科技股份有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-105248458-A | Powdered valerian mosquito-repellent incense and preparation method thereof | LIANG JUN | 2016-01-20 | — | — | CN | disclosed |