Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2102631 | 0.73 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL2104088 | 0.70 | — | — | |
| SCHEMBL31284940 | 0.68 | HRH3 (0.47) | CYP3A4 | |
| SCHEMBL2104378 | 0.66 | HTR2A (0.32) | — | |
| SCHEMBL29678611 | 0.65 | CA12 (0.33) | CYP3A4 | |
| SCHEMBL7482318 | 0.65 | MAOB (0.36) | CYP3A4 | |
| SCHEMBL31305973 | 0.65 | MAOB (0.36) | CYP3A4 | |
| SCHEMBL8800540 | 0.60 | MAOB (0.33) | — | |
| SCHEMBL7487069 | 0.59 | MAOB (0.38) | CYP3A4 | |
| SCHEMBL7348302 | 0.59 | MAOB (0.49) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981880-A2 | USE OF 4-IMIDAZOLE DERIVATIVES FOR CNS DISORDERS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007085556-A2 | USE OF 4-IMIDAZOLE DERIVATIVES FOR CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-02 | — | — | WO | disclosed |