Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305973 | 0.93 | MAOB (0.36) | MAOBXDHSLC22A12MAOAESR2 | |
| SCHEMBL7482318 | 0.93 | MAOB (0.36) | MAOBXDHSLC22A12MAOAESR2 | |
| SCHEMBL2104378 | 0.92 | HTR2A (0.32) | MAOBESR1ESR2 | |
| SCHEMBL3372189 | 0.71 | MAOB (0.46) | MAOBXDHSLC22A12MAOA | |
| SCHEMBL23218980 | 0.70 | PTPN1 (0.31) | MAOB | |
| SCHEMBL29592780 | 0.70 | PTPN1 (0.31) | MAOB | |
| SCHEMBL16426152 | 0.69 | GPR35 (0.37) | MAOBMAOA | |
| SCHEMBL21438364 | 0.69 | MEN1 (0.34) | MAOA | |
| SCHEMBL21438585 | 0.69 | — | — | |
| SCHEMBL7480987 | 0.68 | PKM (0.51) | XDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783499-A1 | BENZOFURAN DERIVATIVES AS TACHYKININ ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1997-07-16 | — | — | EP | disclosed |
| WO-1995006645-A1 | BENZOFURAN DERIVATIVES AS TACHYKININ ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1995-03-09 | — | — | WO | disclosed |