Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818821 | 0.76 | TSHR (0.35) | SLC6A3CHRM3LMNA | |
| SCHEMBL819397 | 0.76 | CHRM3 (0.35) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL459785 | 0.74 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL17145407 | 0.74 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL17145433 | 0.71 | CA12 (0.31) | LMNA | |
| SCHEMBL461375 | 0.71 | ATM (0.36) | SLC6A3LMNA | |
| SCHEMBL17145405 | 0.71 | ATM (0.36) | SLC6A3LMNA | |
| SCHEMBL459862 | 0.68 | PSEN1 (0.34) | SLC6A3 | |
| SCHEMBL17145406 | 0.68 | PSEN1 (0.34) | SLC6A3 | |
| SCHEMBL459352 | 0.67 | ATM (0.40) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011864-A1 | BICYCLIC COMPOUNDS AND PROCESS FOR PREPARATION | PARTNERS FÖR UTVECKLINGSINVESTERINGAR INOM LIFE SCIENCES, P.U.L.S. AB (SE) | 2012-01-26 | — | — | WO | disclosed |