Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.67 |
| ▸ | MMP8 | P22894 | 4/20 | 0.67 |
| ▸ | MMP2 | P08253 | 3/20 | 0.67 |
| ▸ | ACE | P12821 | 3/20 | 0.66 |
| ▸ | ECE1 | P42892 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP3 | P08254 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036184 | 0.94 | ACE (0.69) | MMP9MMP8ACEECE1ALOX15 | |
| SCHEMBL31036035 | 0.89 | ACE (0.71) | ACEECE1ALOX15LTA4H | |
| SCHEMBL30645700 | 0.87 | ERAP2 (0.71) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL30369009 | 0.87 | ERAP2 (0.71) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL30999641 | 0.84 | ACE (0.62) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL31036126 | 0.84 | ECE1 (0.79) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL8357553 | 0.84 | ACE (0.72) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL30999527 | 0.84 | ACE (0.62) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL30368556 | 0.84 | ACE (0.64) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL31036175 | 0.84 | ACE (0.78) | ACEECE1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471881-B1 | USE OF A COMPOUND INACTIVATING THE KINASE A PROTEIN IN A COMPOSITION CONTAINING A COSMETICALLY ACCEPTABLE MEDIUM IN ORDER TO LIGHTEN THE SKIN | SEPPIC SA (FR) | 2008-10-15 | — | — | EP | disclosed |