Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.72 |
| ▸ | ECE1 | P42892 | 12/20 | 0.63 |
| ▸ | MMP2 | P08253 | 2/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | MMP8 | P22894 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036175 | 0.91 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL8357061 | 0.91 | ACE (0.60) | ACEECE1MMP2MMP9MMP8 | |
| SCHEMBL8356994 | 0.86 | ERAP2 (0.63) | ACEMMP2MMP9MMP8 | |
| SCHEMBL11409507 | 0.86 | ACE (0.76) | ACEECE1ALOX15 | |
| SCHEMBL29674960 | 0.85 | ACE (0.64) | ACEECE1ALOX15 | |
| SCHEMBL29429278 | 0.85 | ACE (0.64) | ACEECE1ALOX15 | |
| SCHEMBL29640339 | 0.85 | ACE (0.64) | ACEECE1ALOX15 | |
| SCHEMBL29429277 | 0.85 | ACE (0.64) | ACEECE1ALOX15 | |
| SCHEMBL8358360 | 0.85 | MMP2 (0.59) | ACEECE1MMP2MMP9MMP8 | |
| SCHEMBL8354772 | 0.85 | MMP2 (0.59) | ACEECE1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003017924-A2 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | CUBIST PHARMACEUTICALS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |