SCHEMBL4610370

SCHEMBL4610370

CC(=O)Oc1ccc2cc(Br)ccc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 1/20 0.67
LMNA P02545 5/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
TDP1 Q9NUW8 2/20 0.55
MAPT P10636 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
ATM Q13315 1/20 0.55
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
KDM4E B2RXH2 3/20 0.51
GLA P06280 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
CYP3A4 P08684 3/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.51
FLT3 P36888 2/20 0.50
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29624638 1.00 NCEH1 (0.67) NCEH1LMNAL3MBTL1TDP1MAPT
SCHEMBL27539249 0.96 NCEH1 (0.63) NCEH1LMNAL3MBTL1TDP1MAPT
SCHEMBL30595409 0.88 CA12 (0.65) LMNATDP1MAPTSMN1; SMN2CA12
SCHEMBL3974361 0.88 CA12 (0.65) LMNATDP1MAPTSMN1; SMN2CA12
SCHEMBL29705954 0.84 CA12 (0.61) LMNATDP1MAPTSMN1; SMN2CA12
SCHEMBL5352558 0.84 CA12 (0.61) LMNATDP1MAPTSMN1; SMN2CA12
SCHEMBL10824192 0.82 NCEH1 (0.59) NCEH1LMNAL3MBTL1TDP1MAPT
SCHEMBL154474 0.81 LMNA (0.64) LMNAMAPTSMN1; SMN2RAB9AKDM4E
SCHEMBL25305363 0.81 NCEH1 (0.62) NCEH1LMNAL3MBTL1TDP1MAPT
SCHEMBL829867 0.80 NCEH1 (1.00) NCEH1LMNAL3MBTL1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11414641-B2 Article and method for detecting aerobic bacteria 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-08-16 US disclosed
CN-110709469-B Polycarbonate resin composition, molded article, polycarbonate resin, and end-capping agent for polycarbonate resin 三菱瓦斯化学株式会社 2022-04-29 CN disclosed
US-20210087516-A1 ARTICLE AND METHOD FOR DETECTING AEROBIC BACTERIA 3M INNOVATIVE PROPERTIES COMPANY 2021-03-25 US disclosed
EP-2951279-B1 METHOD AND CULTURE DEVICE FOR DETECTING YEASTS AND MOLDS 3M INNOVATIVE PROPERTIES CO (US) 2020-12-09 EP disclosed
US-10640743-B2 Method and culture device for detecting yeasts and molds 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-05-05 US disclosed
EP-3632983-A1 POLYCARBONATE RESIN COMPOSITION, MOLDED ARTICLE, POLYCARBONATE RESIN, AND TERMINAL-BLOCKING AGENT FOR POLYCARBONATE RESIN Mitsubishi Gas Chemical Company, Inc. (JP) 2020-04-08 EP disclosed
CN-110709469-A Polycarbonate resin composition, molded article, polycarbonate resin, and end-capping agent for polycarbonate resin 三菱瓦斯化学株式会社 2020-01-17 CN disclosed
EP-3553163-A1 ARTICLE AND METHOD FOR DETECTING AEROBIC BACTERIA 3M Innovative Properties Company (US) 2019-10-16 EP disclosed
EP-3114209-B1 ARTICLE AND METHOD FOR DETECTING AEROBIC BACTERIA 3M INNOVATIVE PROPERTIES CO (US) 2019-06-12 EP disclosed
US-20180148675-A1 METHOD AND CULTURE DEVICE FOR DETECTING YEASTS AND MOLDS JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-05-31 US disclosed
CN-101678011-B Spiro-indolinone compounds MERCK SHARP & DOHME 2012-07-18 CN disclosed
EP-0870054-B1 METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS BIOCONTROL SYSTEMS INC (US) 2008-07-30 EP disclosed
CN-100387576-C Substituted phenylalkanoic acid derivatives and use thereof ASAHI CHEMICAL IND (JP) 2008-05-14 CN disclosed
CN-1653032-A Substituted phenylalkanoic acid derivatives and use thereof ASAHI CHEMICAL IND (JP) 2005-08-10 CN disclosed
US-6472167-B1 MEASURE VIABLE BACTERIA AS A FUNCTION OF THE ACTIVITIES OF BACTERIAL ENZYMES, PHOSPHATASES, GLUCOSIDASES, AND AMINOPEPTIDASES; PRESENCE DETECTED BY A FLUORESCENT SIGNAL BIOCONTROL SYSTEMS, INC. 2002-10-29 US disclosed
US-6387650-B1 INNOCULATING AND INCUBATING TEST SAMPLE ON GROWTH MEDIUM HAVING ENZYME SUBSTRATES FOR PHOSPHATASE, GLYCOSIDASE, AND PEPTIDASE, THEN DETECTING OR MEASURING SIGNAL PRODUCED BY THE HYDROLYSIS OF THE SUBSTRATES BIOCONTROL SYSTEMS, INC. 2002-05-14 US disclosed
US-5256829-A Reacting with molecular hydrogen or precursor in acidic organic solvent using tungsten carbide catalyst POTASSE ET PRODUITS CHIMIQUES (FR) 1993-10-26 US disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
US-4374262-A Preparation of hydroxy aromatic carboxylic acids and ester derivatives thereof CELANESE CORPORATION (US) 1983-02-15 US disclosed
EP-0049616-A1 Preparation of hydroxy aromatic carboxylic acids and ester derivatives thereof CELANESE CORPORATION (US) 1982-04-14 EP disclosed