Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 17/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612664 | 0.81 | ACLY (0.62) | ACLYCA1CA2 | |
| SCHEMBL12626450 | 0.75 | ACLY (0.59) | ACLYCA1CA2F2PRSS1 | |
| SCHEMBL10068284 | 0.74 | ACLY (0.62) | ACLYCA1CA2 | |
| SCHEMBL6809423 | 0.74 | CNR1 (0.42) | — | |
| SCHEMBL4610646 | 0.72 | ACLY (0.67) | ACLYCA1CA2 | |
| SCHEMBL4610642 | 0.72 | ACLY (0.67) | ACLYCA1CA2 | |
| SCHEMBL4612655 | 0.72 | ACLY (0.67) | ACLYCA1CA2 | |
| SCHEMBL10037141 | 0.71 | ACLY (0.58) | ACLYCA1CA2F2PRSS1 | |
| SCHEMBL4611818 | 0.71 | ACLY (0.54) | ACLYCA1CA2F2PRSS1 | |
| SCHEMBL4611418 | 0.71 | ACLY (0.62) | ACLYCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981845-A2 | SULFONAMIDE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092558-A2 | SULFONAMIDE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2007-08-16 | — | — | WO | claimed |
| EP-1981845-A2 | SULFONAMIDE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007092558-A2 | SULFONAMIDE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2007-08-16 | — | — | WO | disclosed |