Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15819993 | 0.71 | CTSS (0.35) | MEN1KMT2A | |
| SCHEMBL12068002 | 0.69 | — | — | |
| SCHEMBL7077560 | 0.67 | MEN1 (0.31) | MEN1KMT2ATP53 | |
| SCHEMBL6417020 | 0.67 | — | — | |
| SCHEMBL11651640 | 0.67 | POLB (0.33) | MEN1KMT2ATP53 | |
| SCHEMBL8733232 | 0.67 | POLB (0.33) | CYP2D6CYP2C19MEN1KMT2ATP53 | |
| SCHEMBL1903527 | 0.66 | — | — | |
| Diisopropanolamine SCHEMBL29053431 | 0.66 | CYP2D6 (0.42) | CYP2D6CYP2C19MEN1KMT2ATP53 | |
| SCHEMBL3115481 | 0.64 | — | — | |
| SCHEMBL1982391 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981848-A2 | 11-BETA HSD1 INHIBITORS | Wyeth (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007092435-A2 | 11-BETA HSD1 INHIBITORS | WYETH (US) | 2007-08-16 | — | — | WO | disclosed |