SCHEMBL4610995

SCHEMBL4610995

CC(=O)C12CCCCC1CCCC2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
LMNA P02545 2/20 0.44
TSHR P16473 2/20 0.44
ABCB11 O95342 1/20 0.44
CYP1A2 P05177 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
CHRM3 P20309 1/20 0.44
DRD1 P21728 1/20 0.44
HRH2 P25021 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HRH1 P35367 1/20 0.44
DRD3 P35462 1/20 0.44
SCN1A P35498 1/20 0.44
THPO P40225 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4610996 1.00 CYP3A4 (0.44) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL7251246 0.98 CYP3A4 (0.42) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL21253998 0.98 CYP3A4 (0.46) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL12928713 0.93 CYP3A4 (0.42) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL15116857 0.91 CYP3A4 (0.40) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL19035547 0.86 CYP3A4 (0.38) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL15116547 0.86 CYP3A4 (0.38) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL15116809 0.82
SCHEMBL7244255 0.79 MAPT (0.33) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL17878109 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113286776-A Bicyclic and tricyclic compounds useful as fragrance chemicals 巴斯夫欧洲公司 2021-08-20 CN disclosed
EP-0990634-B1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES DAICEL CHEM (JP) 2013-04-10 EP disclosed
EP-1055654-B1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS DAICEL CHEM (JP) 2008-02-20 EP disclosed
US-7183423-B1 Process for the preparation of organic compounds with imide catalysts DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-02-27 US disclosed
CN-1211333-C Alicyclic compounds containing hydroxymethyl group, process for producing the same, and polymerizable alicyclic compound DAICCL CHEMICAL IND LTD (JP) 2005-07-20 CN disclosed
US-6576787-B1 Hydroxymethyl-group-containing alicyclic compound and process for producing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-10 US disclosed
US-6429314-B1 USING 1,2-DICARBONYL DERIVATIVE OR ITS HYDROXY REDUCTIVE, OXYGEN, COBALT ACETATE METAL COMPOUND, AND N-HYDROXYPHTHALIMIDE OR OTHER IMIDE DERIVATIVE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-06 US disclosed
CN-1293649-A Hydroxymethyl-containing alicyclic compound, process for producing the same, and polymerizable alicyclic compound OAICAL CHEMIAL IND LTD (JP) 2001-05-02 CN disclosed
EP-1070699-A1 ALICYCLIC COMPOUNDS CONTAINING HYDROXYMETHYL GROUP, PROCESS FOR PRODUCING THE SAME, AND POLYMERIZABLE ALICYCLIC COMPOUND Daicel Chemical Industries, Ltd. (JP) 2001-01-24 EP disclosed
EP-1055654-A1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS Daicel Chemical Industries, Ltd. (JP) 2000-11-29 EP disclosed
EP-0990634-A1 ACYLATING AGENTS, ACYLATION METHOD WITH THE USE OF THE SAME AND ADAMANTANE DERIVATIVES Daicel Chemical Industries, Ltd. (JP) 2000-04-05 EP disclosed