Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248360 | 0.89 | MAPT (0.42) | MAPTTSHRMEN1MAPK1KMT2A | |
| SCHEMBL22417651 | 0.81 | MAPT (0.32) | MAPT | |
| SCHEMBL7251594 | 0.79 | — | — | |
| SCHEMBL4610995 | 0.79 | CYP3A4 (0.44) | MAPTCYP3A4TSHRABCB11LMNA | |
| SCHEMBL4610996 | 0.79 | CYP3A4 (0.44) | MAPTCYP3A4TSHRABCB11LMNA | |
| SCHEMBL21253998 | 0.77 | CYP3A4 (0.46) | MAPTCYP3A4TSHRABCB11LMNA | |
| SCHEMBL7251246 | 0.77 | CYP3A4 (0.42) | CYP3A4TSHRABCB11LMNACYP1A2 | |
| SCHEMBL19035547 | 0.76 | CYP3A4 (0.38) | CYP3A4TSHRABCB11LMNACYP1A2 | |
| SCHEMBL15116547 | 0.76 | CYP3A4 (0.38) | CYP3A4TSHRABCB11LMNACYP1A2 | |
| SCHEMBL7251920 | 0.75 | HSD11B1 (0.30) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576787-B1 | Hydroxymethyl-group-containing alicyclic compound and process for producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1070699-A1 | ALICYCLIC COMPOUNDS CONTAINING HYDROXYMETHYL GROUP, PROCESS FOR PRODUCING THE SAME, AND POLYMERIZABLE ALICYCLIC COMPOUND | Daicel Chemical Industries, Ltd. (JP) | 2001-01-24 | — | — | EP | disclosed |