Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 6/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | SELE | P16581 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083411 | 0.80 | EGFR (0.49) | EGFRSELPAPPKDM4ENPC1 | |
| SCHEMBL2083408 | 0.80 | EGFR (0.49) | EGFRSELPAPPKDM4ENPC1 | |
| SCHEMBL4228293 | 0.80 | EGFR (0.49) | EGFRSELPAPPKDM4ENPC1 | |
| SCHEMBL2085821 | 0.79 | EGFR (0.47) | EGFRSELPAPPKDM4ENPC1 | |
| SCHEMBL2085824 | 0.79 | EGFR (0.47) | EGFRSELPAPPKDM4ENPC1 | |
| SCHEMBL2083594 | 0.78 | SELP (0.46) | EGFRSELPAPPKDM4ENPC1 | |
| SCHEMBL2083592 | 0.78 | SELP (0.46) | EGFRSELPAPPKDM4ENPC1 | |
| SCHEMBL3200016 | 0.77 | NAAA (0.50) | EGFRALDH1A1LTB4R2NAAA | |
| SCHEMBL4611217 | 0.77 | APP (0.48) | EGFRSELPAPP | |
| SCHEMBL4611221 | 0.77 | APP (0.48) | EGFRSELPAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | disclosed |