SCHEMBL4612170

SCHEMBL4612170

O=C(O)C(Cl)=CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3322795 0.75 THRB (0.41) THRB
SCHEMBL2785405 0.75 THRB (0.41) THRB
SCHEMBL15754626 0.75 THRB (0.41) THRB
SCHEMBL3313856 0.75 THRB (0.41) THRB
SCHEMBL7004102 0.75 THRB (0.41) THRB
SCHEMBL534526 0.75 THRB (0.41) THRB
SCHEMBL830694 0.75 THRB (0.41) THRB
SCHEMBL222705 0.75 THRB (0.41) THRB
SCHEMBL22204284 0.75 THRB (0.41) THRB
SCHEMBL3315869 0.75 THRB (0.41) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1247820-B1 Method of preparing polymer particles having narrow particle size distribution AGFA GRAPHICS NV (BE) 2008-02-27 EP disclosed
US-6800709-B2 MONODISPERSE POLYMERS BY FREE RADICAL POLYMERIZATION OR COPOLYMERIZATION OF HYDROPHOBIC MONOMERS IN WATER-BASED SYSTEMS IN THE PRESENCE OF CYCLODEXTRIN AGFA-GEVAERT N.V. (BE) 2004-10-05 US disclosed
US-20020173610-A1 Method of preparing polymer particles having narrow particle size distribution AGFA GRAPHICS NV (BE) 2002-11-21 US disclosed
EP-1247820-A1 Method of preparing polymer particles having narrow particle size distribution Agfa-Gevaert (BE) 2002-10-09 EP disclosed