Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896643 | 0.93 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| SCHEMBL17897067 | 0.90 | CYP11B2 (0.66) | CYP11B2CYP11B1 | |
| SCHEMBL17896605 | 0.84 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL17896618 | 0.84 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL17896655 | 0.84 | CYP11B2 (0.69) | CYP11B2CYP11B1 | |
| SCHEMBL17896611 | 0.83 | CYP11B2 (0.50) | CYP11B2CYP11B1 | |
| SCHEMBL20337690 | 0.83 | CYP11B2 (0.77) | CYP11B2CYP11B1 | |
| SCHEMBL20338201 | 0.83 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL17897055 | 0.81 | CYP11B2 (0.88) | CYP11B2CYP11B1 | |
| SCHEMBL458680 | 0.80 | CYP11B2 (1.00) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595482-A1 | ALDOSTERONE SYNTHASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-05-29 | — | — | EP | claimed |
| WO-2012012478-A1 | ALDOSTERONE SYNTHASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-01-26 | — | — | WO | claimed |
| US-9382226-B2 | Aldosterone synthase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9382226-B2 | Aldosterone synthase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-07-05 | — | — | US | disclosed |
| WO-2012012478-A1 | ALDOSTERONE SYNTHASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-01-26 | — | — | WO | disclosed |