Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 19/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14289239 | 1.00 | PTGS2 (0.65) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4613075 | 0.81 | PTGS2 (0.63) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7799590 | 0.79 | PTGS2 (0.73) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4611741 | 0.79 | PTGS2 (0.69) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7795840 | 0.78 | PTGS2 (0.70) | PTGS2PTGS1ALOX5 | |
| Hydrochloric Acid SCHEMBL7795844 | 0.78 | PTGS2 (0.71) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7797541 | 0.78 | PTGS2 (0.67) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4612538 | 0.77 | PTGS2 (0.77) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4613977 | 0.76 | PTGS2 (0.65) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4614280 | 0.76 | PTGS2 (0.81) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773939-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2008-02-06 | — | — | EP | disclosed |
| US-5674891-A | ANALGESICS WITH SIDE EFFECT REDUCTION | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5656661-A | ANALGESICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0773939-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003396-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |