Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | RYR1 | P21817 | 2/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612611 | 0.84 | TDP1 (0.31) | RYR1FKBP1A | |
| SCHEMBL2262585 | 0.82 | NR1H2 (0.32) | RYR1FKBP1ANR1H2NR1H3 | |
| SCHEMBL4612280 | 0.77 | — | — | |
| SCHEMBL19912596 | 0.77 | — | — | |
| SCHEMBL14031965 | 0.75 | NR1H2 (0.40) | NR1H2NR1H3PTGS1PTGS2 | |
| SCHEMBL4611348 | 0.75 | DRD2 (0.30) | — | |
| SCHEMBL4612743 | 0.75 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL4612895 | 0.74 | ERN1 (0.30) | — | |
| SCHEMBL4613095 | 0.74 | HTR2A (0.44) | NR1H2NR1H3 | |
| SCHEMBL9732911 | 0.73 | NR1H2 (0.42) | NR1H2NR1H3PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633762-B1 | Paracyclophanes | JOHNSON MATTHEY PLC (GB) | 2008-10-29 | — | — | EP | disclosed |
| US-7256302-B2 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2007-08-14 | — | — | US | disclosed |
| US-7256302-B2 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2007-08-14 | — | — | US | disclosed |
| US-20060229473-A1 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2006-10-12 | — | — | US | disclosed |
| EP-1633762-A1 | LIGANDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004111065-A1 | LIGANDS | JOHNSON MATTHEY PLC (GB) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229473-A1 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | C1S, CCR1, CYC1 | KDM1A 3627/4885RYR1 1705/4885FKBP1A 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.