Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610576 | 0.89 | FFAR4 (0.51) | PTGER1PTGER4PTGER3PTGER2PPIA | |
| SCHEMBL2085323 | 0.88 | FFAR4 (0.44) | PPIAFFAR1SLC1A5RXRARXRB | |
| SCHEMBL2085429 | 0.84 | FFAR4 (0.51) | FFAR1RXRARXRBRXRGS1PR1 | |
| SCHEMBL2081667 | 0.76 | FFAR1 (0.49) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL4612420 | 0.76 | PTGER1 (0.43) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL2084954 | 0.71 | FFAR4 (0.51) | FFAR1KIFC1RXRARXRBRXRG | |
| SCHEMBL4974639 | 0.70 | KMT2A (0.46) | FFAR1RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL4970681 | 0.70 | FFAR4 (0.52) | FFAR1RXRARXRBRXRGMAOB | |
| SCHEMBL20401478 | 0.70 | TP53 (0.54) | TP53RXFP1 | |
| SCHEMBL4969467 | 0.69 | MEN1 (0.54) | FFAR1RXRARXRBRXRGMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | claimed |