Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610356 | 0.89 | FFAR1 (0.51) | MTNR1AMTNR1BFFAR1 | |
| SCHEMBL2085300 | 0.88 | FFAR1 (0.45) | MTNR1AMTNR1BROCK2FFAR1BCHE | |
| SCHEMBL2083300 | 0.85 | FFAR1 (0.50) | MTNR1AMTNR1BFFAR1OPRM1OPRD1 | |
| SCHEMBL2085155 | 0.83 | FFAR1 (0.49) | MTNR1AMTNR1BFFAR1MAOB | |
| SCHEMBL4969516 | 0.81 | FFAR1 (0.47) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL4612375 | 0.77 | PPARA (0.43) | OPRM1OPRD1OPRK1KMT2AALDH1A1 | |
| SCHEMBL4612592 | 0.76 | PTGER1 (0.43) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL2085517 | 0.76 | FFAR1 (0.52) | MTNR1AMTNR1BROCK2FFAR1OPRM1 | |
| SCHEMBL2084534 | 0.75 | FFAR1 (0.49) | PTGER1PTGER4PTGER3PTGER2FFAR1 | |
| SCHEMBL4611227 | 0.75 | KCNH2 (0.45) | ROCK2FFAR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | claimed |