Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.66 |
| ▸ | CTSL | P07711 | 2/20 | 0.64 |
| ▸ | CTSB | P07858 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612848 | 1.00 | CTSK (0.66) | CTSKCTSLCTSB | |
| SCHEMBL4612692 | 0.87 | CTSK (0.70) | CTSKCTSLCTSB | |
| SCHEMBL4612696 | 0.87 | CTSK (0.70) | CTSKCTSLCTSB | |
| SCHEMBL4612755 | 0.84 | CTSK (0.58) | CTSKCTSLCTSB | |
| SCHEMBL4612752 | 0.84 | CTSK (0.58) | CTSKCTSLCTSB | |
| SCHEMBL4616025 | 0.83 | CTSK (0.63) | CTSKCTSLCTSB | |
| SCHEMBL4616028 | 0.83 | CTSK (0.63) | CTSKCTSLCTSB | |
| SCHEMBL8358126 | 0.82 | CTSK (0.94) | CTSKCTSLCTSB | |
| SCHEMBL6141863 | 0.82 | CTSK (0.62) | CTSKCTSLCTSB | |
| SCHEMBL4614110 | 0.80 | CTSK (1.00) | CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446115-B1 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-02-27 | — | — | EP | claimed |
| US-7371747-B2 | Cyanoalkylamino derivatives as protease inhibitors | MERCK FROSST CANADA & CO. (CA) | 2008-05-13 | — | — | US | disclosed |
| US-7371747-B2 | Cyanoalkylamino derivatives as protease inhibitors | MERCK FROSST CANADA & CO. (CA) | 2008-05-13 | — | — | US | disclosed |