Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460922 | 1.00 | CYP2C9 (0.51) | CYP2C9HDAC2PARP10DGAT1MAOB | |
| SCHEMBL460921 | 1.00 | CYP2C9 (0.51) | CYP2C9HDAC2PARP10DGAT1MAOB | |
| SCHEMBL461356 | 1.00 | CYP2C9 (0.51) | CYP2C9HDAC2PARP10DGAT1MAOB | |
| SCHEMBL13255268 | 0.88 | HDAC2 (0.52) | CYP2C9HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL2762400 | 0.82 | CYP2C9 (0.69) | CYP2C9PARP10DGAT1HDAC8HDAC6 | |
| SCHEMBL9303496 | 0.81 | HDAC2 (0.56) | CYP2C9HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL9303509 | 0.81 | HDAC2 (0.56) | CYP2C9HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL9303504 | 0.81 | HDAC2 (0.56) | CYP2C9HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL9303500 | 0.81 | HDAC2 (0.56) | CYP2C9HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL9258155 | 0.81 | CYP2C9 (0.56) | CYP2C9HDAC2PARP10DGAT1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595970-A1 | DERIVATIVES OF OXADIAZOLE AND PYRIDAZINE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012011081-A1 | DERIVATIVES OF OXADIAZOLE AND PYRIDAZINE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |