Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 19/20 | 0.93 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611907 | 0.96 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4612949 | 0.91 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4614280 | 0.86 | PTGS2 (0.81) | PTGS2PTGS1ALOX5 | |
| SCHEMBL441830 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4612538 | 0.82 | PTGS2 (0.77) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4612116 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4613560 | 0.81 | PTGS2 (0.75) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4611762 | 0.81 | PTGS2 (0.83) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4612408 | 0.80 | PTGS2 (0.77) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4613406 | 0.80 | PTGS2 (0.73) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773939-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2008-02-06 | — | — | EP | disclosed |
| US-5674891-A | ANALGESICS WITH SIDE EFFECT REDUCTION | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5656661-A | ANALGESICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |