Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461845 | 0.90 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL3824352 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL461576 | 0.85 | PTGS2 (0.87) | PTGS2PTGS1 | |
| SCHEMBL10092132 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3826261 | 0.85 | PTGS2 (0.86) | PTGS2PTGS1 | |
| SCHEMBL461575 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL15052396 | 0.84 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL15072600 | 0.83 | PTGS2 (0.88) | PTGS2PTGS1 | |
| SCHEMBL17453259 | 0.83 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL3826265 | 0.82 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614050-A1 | 1,5-DIARYL-2-ALKYLPYRROLE-3-SUBSTITUTED NITRO ESTERS, SELECTIVE COX-2 INHIBITORS AND NITRIC OXIDE DONORS | Rottapharm S.p.A. (IT) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032479-A1 | L,5-DIARYL-2-ALKVLPVRROLE-3-SUBSTITUTED NITRO ESTERS, SELECTIVE COX-2 INHIBITORS AND NITRIC OXIDE DONORS | ROTTAPHARM S.P.A. (IT) | 2012-03-15 | — | — | WO | disclosed |