Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612215 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAPTCYP3A4CYP1A2TYMS | |
| SCHEMBL22028064 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP3A4CYP1A2TYMS | |
| SCHEMBL30997742 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP3A4CYP1A2TYMS | |
| SCHEMBL14441391 | 0.79 | HSD17B10 (0.42) | ALDH1A1MAPTCYP3A4CYP1A2HSD17B10 | |
| SCHEMBL3519263 | 0.78 | MAPT (0.57) | ALDH1A1MAPTCYP3A4CYP1A2TYMS | |
| SCHEMBL17971149 | 0.74 | HTR2A (0.34) | ALDH1A1MAPT | |
| SCHEMBL34474086 | 0.72 | MAPT (0.51) | ALDH1A1MAPTCYP3A4CYP1A2TYMS | |
| SCHEMBL7162505 | 0.72 | TYMS (0.53) | ALDH1A1MAPTCYP3A4CYP1A2TYMS | |
| SCHEMBL1090688 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4CYP1A2TYMS | |
| SCHEMBL19046358 | 0.71 | TYMS (0.49) | ALDH1A1MAPTCYP3A4CYP1A2TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633762-B1 | Paracyclophanes | JOHNSON MATTHEY PLC (GB) | 2008-10-29 | — | — | EP | disclosed |
| US-7256302-B2 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2007-08-14 | — | — | US | disclosed |
| US-7256302-B2 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2007-08-14 | — | — | US | disclosed |
| US-7256302-B2 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2007-08-14 | — | — | US | disclosed |
| US-20060229473-A1 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | JOHNSON MATTHEY PLC (GB) | 2006-10-12 | — | — | US | disclosed |
| EP-1633762-A1 | LIGANDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004111065-A1 | LIGANDS | JOHNSON MATTHEY PLC (GB) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229473-A1 | Catalyst ligand with groups on one or both of the benzene rings in a paracyclophane structure; high activity and selectivity for asymmetric reactions, facilitate chiral resolution | C1S, CCR1, CYC1 | ALDH1A1 912/4885MAPT 4832/4885CYP3A4 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.