Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.64 |
| ▸ | PPARG | P37231 | 11/20 | 0.64 |
| ▸ | PPARA | Q07869 | 11/20 | 0.64 |
| ▸ | CLK1 | P49759 | 2/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.52 |
| ▸ | SENP5 | Q96HI0 | 2/20 | 0.52 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | GNA15 | P30679 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616927 | 0.90 | PPARA (0.69) | PPARDPPARGPPARACLK1SENP1 | |
| SCHEMBL4616850 | 0.85 | PPARG (0.63) | PPARDPPARGPPARASENP1SENP5 | |
| SCHEMBL4614402 | 0.83 | PPARG (0.68) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL4616709 | 0.80 | PPARG (0.81) | PPARDPPARGPPARA | |
| SCHEMBL4616373 | 0.80 | PPARG (0.65) | PPARDPPARGPPARAFFAR1 | |
| SCHEMBL4614376 | 0.80 | PPARG (0.75) | PPARDPPARGPPARA | |
| SCHEMBL4616350 | 0.78 | PPARG (1.00) | PPARDPPARGPPARAFFAR1GNA15 | |
| SCHEMBL4616583 | 0.78 | PPARG (0.62) | PPARDPPARGPPARASENP1FFAR1 | |
| SCHEMBL4617164 | 0.78 | PPARG (0.73) | PPARDPPARGPPARASENP1SENP5 | |
| SCHEMBL4617026 | 0.77 | PPARG (0.65) | PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (IN) | 2007-04-12 | — | — | US | disclosed |
| EP-1697304-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054176-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082907-A1 | Peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | PPARD 3/4885PPARG 1/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.