Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461481 | 1.00 | KDM1A (0.37) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL462830 | 0.92 | KDM1A (0.39) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL170772 | 0.92 | KDM1A (0.39) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL148173 | 0.92 | KDM1A (0.39) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL458267 | 0.85 | KDM1A (0.39) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL146482 | 0.84 | KDM1A (0.40) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL145666 | 0.84 | FPR1 (0.44) | KDM1AEPHX2MAOBMAOAFPR1 | |
| SCHEMBL146484 | 0.84 | KDM1A (0.40) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL146483 | 0.84 | KDM1A (0.40) | KDM1AEPHX2NFKB1NFKB2RELA | |
| SCHEMBL145665 | 0.84 | FPR1 (0.44) | KDM1AEPHX2MAOBMAOAFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |