SCHEMBL4614892

SCHEMBL4614892

O=C(O)c1ccc2[nH]nnc2c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
DHODH Q02127 7/20 0.40
HNF4A P41235 3/20 0.40
ACMSD Q8TDX5 2/20 0.40
KDM4E B2RXH2 6/20 0.38
TP53 P04637 1/20 0.38
WDR5 P61964 1/20 0.38
HPGD P15428 2/20 0.37
GFER P55789 2/20 0.37
MAPT P10636 1/20 0.37
PIM1 P11309 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GPR35 Q9HC97 1/20 0.37
DHFR P00374 1/20 0.37
MCL1 Q07820 1/20 0.37
KDM6B O15054 1/20 0.36
KDM6A O15550 1/20 0.36
TET3 O43151 1/20 0.36
KDM4A O75164 1/20 0.36
KDM4B O94953 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19148216 0.84 PADI4 (0.39) ALDH1A1DHODHKDM4ETP53HPGD
SCHEMBL29359068 0.82 CHEK1 (0.37) MAPTGPR35HTT
SCHEMBL80394 0.82 CHEK1 (0.37) MAPTGPR35HTT
SCHEMBL8836008 0.81 CHEK1 (0.36) MAPTGPR35HTT
SCHEMBL6897857 0.81 CHEK1 (0.36) MAPTGPR35HTT
SCHEMBL27412736 0.77 AKT2 (0.38) KMT2A
SCHEMBL8953072 0.77 CYP1A2 (0.35) ALDH1A1KDM4EHPGDKDM6BKDM6A
SCHEMBL6052102 0.77 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMAPTPIM1
SCHEMBL10449195 0.76 KDM4E (0.38) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL28715894 0.76 GSK3B (0.39) MAPTL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462295-B1 Onament and indicator panel for vehicle interior CALSONIC KANSEI CORP (JP) 2008-01-23 EP claimed
US-20040228986-A1 Interior ornament and indicator panel for vehicle CALSONIC KANSEI CORPORATION (JP) 2004-11-18 US claimed
EP-1462295-A2 Onament and indicator panel for vehicle interior Calsonic Kansei Corporation (JP) 2004-09-29 EP claimed
US-20170210903-A1 FLUORESCENT DYE COMPOUND HAVING BENZOTRIAZOLE STRUCTURE AND WAVELENGTH-CONVERTING ENCAPSULANT COMPOSITION USING SAME NITTO DENKO CORPORATION (JP) 2017-07-27 US disclosed
US-20170198143-A1 FLUORESCENT DYE COMPOUND HAVING BENZOTRIAZOLE STRUCTURE, POLYMER FLUORESCENT DYE COMPOUND AND WAVELENGTH-CONVERTING ENCAPSULANT COMPOSITION USING SAME NITTO DENKO CORPORATION (JP) 2017-07-13 US disclosed
EP-1462295-B1 Onament and indicator panel for vehicle interior CALSONIC KANSEI CORP (JP) 2008-01-23 EP disclosed
US-20040228986-A1 Interior ornament and indicator panel for vehicle CALSONIC KANSEI CORPORATION (JP) 2004-11-18 US disclosed
EP-1462295-A2 Onament and indicator panel for vehicle interior Calsonic Kansei Corporation (JP) 2004-09-29 EP disclosed
JP-2001088430-A INK JET RECORDING MATERIAL KIMOTO & CO LTD 2001-04-03 JP disclosed