SCHEMBL4615004

SCHEMBL4615004

O=C(O)C(=O)C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.45
CPT1B Q92523 1/20 0.44
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
ESR1 P03372 7/20 0.42
ESR2 Q92731 6/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA3 P07451 2/20 0.42
TYR P14679 2/20 0.42
CA4 P22748 2/20 0.42
CA5A P35218 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
DRD1 P21728 2/20 0.42
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
CA6 P23280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180939 0.80 SRC (0.54) SRCCPT1BCNR1CNR2ESR1
SCHEMBL11493122 0.80 TDP1 (0.56) SRCCNR1CNR2ALDH1A1KMT2A
SCHEMBL6054379 0.79 SRC (0.48) SRCCPT1BESR1ESR2CA12
SCHEMBL27473645 0.78 SRC (0.52) SRCCPT1BCNR1CNR2ESR1
SCHEMBL27577340 0.78 SRC (0.52) SRCCPT1BCNR1CNR2ESR1
SCHEMBL29182115 0.77 SRC (0.48) SRCCPT1BESR1ESR2CA12
SCHEMBL19433875 0.77 SRC (0.42) SRCCPT1BESR1ESR2CA12
SCHEMBL9577440 0.77 ESR1 (0.50) SRCCPT1BESR1ESR2CA12
SCHEMBL5843647 0.77 ESR1 (0.48) SRCCNR1CNR2ESR1ESR2
SCHEMBL2942876 0.74 CNR1 (0.54) SRCCNR1CNR2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1294913-B1 CHANGING THE FINE CHEMICAL CONTENT IN ORGANISMS BY GENETICALLY MODIFYING THE SHIKIMATE PATHWAY SUNGENE GMBH & CO KGAA (DE) 2008-03-12 EP disclosed
EP-1294913-A1 CHANGING THE FINE CHEMICAL CONTENT IN ORGANISMS BY GENETICALLY MODIFYING THE SHIKIMATE PATHWAY Sungene GmbH & Co. KGaA (DE) 2003-03-26 EP disclosed
WO-2002000901-A1 CHANGING THE FINE CHEMICAL CONTENT IN ORGANISMS BY GENETICALLY MODIFYING THE SHIKIMATE PATHWAY SUNGENE GMBH & CO. KGAA (DE) 2002-01-03 WO disclosed