Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577330 | 0.84 | CYP2C9 (0.52) | ESR1PTGS2CYP2C9PTGS1LMNA | |
| SCHEMBL9577465 | 0.83 | ALOX5 (0.44) | ESR1PTGS2CYP2C9SMN1; SMN2PTGS1 | |
| SCHEMBL288003 | 0.82 | PTGS2 (0.63) | ESR1ESR2PDCD1CD274PTGS2 | |
| SCHEMBL7973447 | 0.82 | PTGS2 (0.52) | PTGS2MAPTCYP3A4SMN1; SMN2SRC | |
| SCHEMBL29273241 | 0.82 | PTGS2 (0.52) | PTGS2MAPTCYP3A4SMN1; SMN2SRC | |
| SCHEMBL1345582 | 0.82 | PTGS2 (0.63) | ESR1ESR2PDCD1CD274PTGS2 | |
| SCHEMBL851630 | 0.82 | PTGS2 (0.52) | PTGS2MAPTCYP3A4SMN1; SMN2SRC | |
| SCHEMBL892055 | 0.82 | PTGS2 (0.63) | ESR1ESR2PDCD1CD274PTGS2 | |
| SCHEMBL10443227 | 0.81 | GRM7 (0.44) | ESR1PTGS2CYP2C9PTGS1LMNA | |
| SCHEMBL9577333 | 0.81 | BRD4 (0.47) | ESR1PTGS2CYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |