Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCK1 | P35558 | 16/20 | 0.59 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615981 | 0.89 | PCK1 (0.59) | PCK1 | |
| SCHEMBL4613198 | 0.88 | PCK1 (0.45) | PCK1 | |
| SCHEMBL4612921 | 0.88 | PCK1 (0.58) | PCK1JAK1 | |
| SCHEMBL4615362 | 0.87 | PCK1 (0.60) | PCK1 | |
| SCHEMBL4614243 | 0.87 | PCK1 (0.53) | PCK1 | |
| SCHEMBL4614233 | 0.86 | PCK1 (0.47) | PCK1KMT2A | |
| SCHEMBL4615633 | 0.85 | PCK1 (0.59) | PCK1 | |
| SCHEMBL4612956 | 0.85 | PCK1 (0.55) | PCK1 | |
| SCHEMBL4614242 | 0.84 | PCK1 (0.58) | PCK1 | |
| SCHEMBL4612950 | 0.84 | PCK1 (0.45) | PCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599477-B1 | SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-30 | — | — | EP | claimed |