Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 9/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615763 | 1.00 | CHRM4 (0.36) | CHRM4PANK3KCNJ1 | |
| SCHEMBL4940333 | 0.80 | ALDH1A1 (0.37) | CHRM4PANK3 | |
| SCHEMBL4634019 | 0.77 | MC4R (0.50) | — | |
| SCHEMBL4612691 | 0.69 | TACR3 (0.38) | CHRM4PANK3 | |
| SCHEMBL4612979 | 0.67 | MC4R (0.44) | — | |
| SCHEMBL4601335 | 0.67 | MC4R (0.52) | — | |
| SCHEMBL4932674 | 0.67 | MC4R (0.52) | — | |
| SCHEMBL4601984 | 0.66 | ALDH1A1 (0.37) | — | |
| SCHEMBL4603038 | 0.66 | MC4R (0.51) | — | |
| SCHEMBL4602361 | 0.66 | MC4R (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912968-A1 | PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS | Pfizer Limited (GB) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015162-A1 | PIPERIDINOYL-PYRROLIDINE AND PIPERIDINOYL-PIPERIDINE COMPOUNDS | PFIZER LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |