Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554172 | 0.81 | NAMPT (0.42) | AVPR2AVPR1A | |
| SCHEMBL4616626 | 0.79 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL5890736 | 0.76 | AVPR2 (0.43) | AVPR2AVPR1A | |
| SCHEMBL3555113 | 0.75 | NAMPT (0.40) | AVPR2 | |
| SCHEMBL3554157 | 0.75 | DGAT2 (0.44) | AVPR2 | |
| SCHEMBL3550256 | 0.75 | USP2 (0.45) | AVPR2 | |
| SCHEMBL3535323 | 0.75 | AVPR2 (0.49) | AVPR2AVPR1A | |
| SCHEMBL3559955 | 0.75 | NAMPT (0.41) | — | |
| SCHEMBL6207415 | 0.75 | AVPR2 (0.39) | AVPR2AVPR1AHTR2C | |
| SCHEMBL5835303 | 0.75 | AVPR1A (0.51) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879897-A1 | PYRROLOBENZODIAZEPINES AND HETEROARYL, ARYL AND CYCLOALKYLAMINO KETONE DERIVATIVES AS FOLLICLE STIMULATING HORMONE RECEPTOR -(FISH-R) ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124523-A1 | PYRROLOBENZODIAZEPINES AND HETEROARYL, ARYL AND CYCLOALKYLAMINO KETONE DERIVATIVES AS FOLLICLE STIMULATING HORMONE RECEPTOR -(FISH-R) ANTAGONISTS | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20060258644-A1 | Pyrrolobenzodiazepines and heteroaryl, aryl and cycloalkylamino ketone derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | WYETH (US) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258644-A1 | Pyrrolobenzodiazepines and heteroaryl, aryl and cycloalkylamino ketone derivatives as follicle stimulating hormone receptor (FSH-R) antagonists | FSHR, GNRHR, PRLHR | AVPR2 13/4885AVPR1A 30/4885HTR2C 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.