Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | STAMBP | O95630 | 1/20 | 0.52 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616068 | 0.89 | MMP13 (0.57) | MMP13MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4614555 | 0.87 | MAPK14 (0.64) | MAPK14STAMBP | |
| SCHEMBL9416562 | 0.85 | MMP13 (0.76) | MMP13MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL5429402 | 0.83 | MMP13 (0.53) | MMP13MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4616524 | 0.83 | PPARG (0.59) | MMP13RAB9ANPC1MAPK14 | |
| SCHEMBL5331977 | 0.83 | MMP13 (0.76) | MMP13MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4615804 | 0.81 | PPARA (0.72) | MMP13 | |
| SCHEMBL18773965 | 0.80 | NPC1 (0.64) | MMP13MEN1KMT2AALDH1A1GAA | |
| SCHEMBL5332456 | 0.79 | MMP13 (0.89) | MMP13MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL5331526 | 0.79 | MMP13 (0.74) | MMP13MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |