Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616169 | 1.00 | EPHX2 (0.45) | EPHX2EPHX1NPC1RAB9ALMNA | |
| SCHEMBL4616167 | 1.00 | EPHX2 (0.45) | EPHX2EPHX1NPC1RAB9ALMNA | |
| SCHEMBL4888026 | 0.87 | EPHX2 (0.46) | EPHX2EPHX1NPC1RAB9ALMNA | |
| SCHEMBL4888037 | 0.87 | EPHX2 (0.46) | EPHX2EPHX1NPC1RAB9ALMNA | |
| SCHEMBL4603422 | 0.80 | EPHX2 (0.47) | EPHX2EPHX1NPC1RAB9A | |
| SCHEMBL4889350 | 0.80 | EPHX2 (0.47) | EPHX2EPHX1NPC1RAB9A | |
| SCHEMBL4880576 | 0.79 | EPHX2 (0.53) | EPHX2 | |
| SCHEMBL2790679 | 0.77 | MMP1 (0.39) | — | |
| SCHEMBL2790678 | 0.77 | MMP1 (0.39) | — | |
| SCHEMBL4603007 | 0.76 | NPC1 (0.41) | NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915342-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2006115353-A1 | A NOVEL HYDROXAMIC ACID DERIVATIVE AS PEPTIDE DEFORMYLASE INHIBITOR AND MANUFACTURING METHOD THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2006-11-02 | — | — | WO | disclosed |