Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SI | P14410 | 2/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701177 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL11422036 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL11118030 | 0.83 | SMN1; SMN2 (0.88) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL188811 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL11111473 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL28741307 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL2855909 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL10601439 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL9784182 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 | |
| SCHEMBL19105452 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1CA14KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076601-A | FROM DIMETHYL MALONATE | MONSANTO COMPANY (US) | 1978-02-28 | — | — | US | claimed |
| US-20210143478-A1 | Electrolyte for Lithium Ion Batteries | Westfälische Wilhelms-Universität Münster (DE) | 2021-05-13 | — | — | US | disclosed |
| EP-3639317-A1 | ELECTROLYTE FOR LITHIUM ION BATTERIES | Westfälische Wilhelms-Universität Münster (DE) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018229109-A1 | ELECTROLYTE FOR LITHIUM ION BATTERIES | Westfälische Wilhelms-Universität Münster (DE) | 2018-12-20 | — | — | WO | disclosed |
| EP-1565419-B1 | METHOD OF PREPARING DI(KETENE ACETALS) | A P PHARMA INC (US) | 2008-04-02 | — | — | EP | disclosed |
| EP-1569664-B1 | BIOERODIBLE POLY(ORTHO ESTERS) FROM DIOXANE-BASED DI(KETENE ACETALS), AND BLOCK COPOLYMERS CONTAINING THEM | A P PHARMA INC (US) | 2008-02-13 | — | — | EP | disclosed |
| CN-100354246-C | Method of preparing di(ketene acetals) | A P PHARMA INC (US) | 2007-12-12 | — | — | CN | disclosed |
| US-7163694-B2 | Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them | A.P. PHARMA, INC. (US) | 2007-01-16 | — | — | US | disclosed |
| EP-1569664-A4 | BIOERODIBLE POLY(ORTHO ESTERS) FROM DIOXANE-BASED DI(KETENE ACETALS), AND BLOCK COPOLYMERS CONTAINING THEM | A P PHARMA INC (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060155101-A1 | Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them | HERON THERAPEUTICS, INC. (F/K/A A.P. PHARMA, INC.) | 2006-07-13 | — | — | US | disclosed |
| US-6863782-B2 | Method of preparing di(ketene acetals) | A.P. PHARMA, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| WO-2004046074-A1 | METHOD OF PREPARING DI(KETENE ACETALS) | A.P. PHARMA, INC. (US) | 2004-06-03 | — | — | WO | disclosed |
| WO-2004046328-A2 | BIOERODIBLE POLY(ORTHO ESTERS) FROM DIOXANE-BASED DI(KETENE ACETALS), AND BLOCK COPOLYMERS CONTAINING THEM | A.P. PHARMA, INC. (US) | 2004-06-03 | — | — | WO | disclosed |
| US-20040096506-A1 | Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them | AP PHARMA, INC. | 2004-05-20 | — | — | US | disclosed |
| US-20040097742-A1 | Method of preparing di(ketene acetals) | HERON THERAPEUTICS, INC. (F/K/A A.P. PHARMA, INC.) | 2004-05-20 | — | — | US | disclosed |
| US-4659441-A | ELECTROLYSIS OF DIETHYL MALONATE | THE DOW CHEMICAL COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| US-4598073-A | Certain polycyclo-palladium-bipyridine complexes having anti-tumor activity | RESEARCH CORPORATION (US) | 1986-07-01 | — | — | US | disclosed |
| EP-0028430-B1 | A PROCESS FOR THE ELECTROREDUCTIVE PREPARATION OF ORGANIC COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |
| EP-0028430-A1 | A process for the electroreductive preparation of organic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-13 | — | — | EP | disclosed |
| US-4076601-A | FROM DIMETHYL MALONATE | MONSANTO COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040096506-A1 | Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them | CYP8B1, OXER1, OXSR1 | SMN1; SMN2 2688/4885ALDH1A1 1482/4885CA14 1901/4885 |
| US-20210143478-A1 | Electrolyte for Lithium Ion Batteries | KCNN2, KCNN1, SLC26A3 | SMN1; SMN2 3501/4885ALDH1A1 1831/4885CA14 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.