Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13782 | 0.87 | DAO (0.48) | TAAR1DAOIDO1MAOBRXRA | |
| SCHEMBL1972143 | 0.84 | DAO (0.46) | TAAR1DAOIDO1MAOBHTR2A | |
| Hydrochloric Acid SCHEMBL966617 | 0.82 | IDO1 (0.47) | TAAR1DAOIDO1MAOBHTR2A | |
| SCHEMBL5426147 | 0.82 | IDO1 (0.61) | TAAR1DAOIDO1MAOBHRH1 | |
| SCHEMBL16950937 | 0.82 | DAO (0.53) | DAOIDO1RXRARXRBRXRG | |
| SCHEMBL25955850 | 0.82 | MAOB (0.49) | TAAR1DAOMAOBRXRARXRB | |
| SCHEMBL22265169 | 0.81 | TAAR1 (0.48) | TAAR1DAOIDO1MAOBHTR1D | |
| Hydrochloric Acid SCHEMBL4496729 | 0.81 | IDO1 (0.64) | TAAR1DAOIDO1MAOBHRH1 | |
| SCHEMBL6815067 | 0.81 | TAAR1 (0.52) | TAAR1DAOIDO1MAOBHTR2A | |
| SCHEMBL12226967 | 0.81 | DAO (0.51) | DAOIDO1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914351-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | Nodthera Limited (GB) | 2021-12-01 | — | — | EP | disclosed |
| WO-2020152361-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-07-30 | — | — | WO | disclosed |
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-1697304-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054176-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |