Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15133743 | 0.85 | ESR1 (0.44) | IDO1DAOHTR2APDE2ACYP1A2 | |
| SCHEMBL4616378 | 0.81 | TAAR1 (0.52) | TAAR1IDO1MAOBDAOHTR2A | |
| SCHEMBL18934899 | 0.81 | MPO (0.43) | TAAR1IDO1DAOHTR2AHTR2C | |
| SCHEMBL5426147 | 0.79 | IDO1 (0.61) | TAAR1IDO1MAOBDAOPDE2A | |
| SCHEMBL20472553 | 0.79 | IDO1 (0.61) | TAAR1IDO1MAOBDAOHTR2A | |
| SCHEMBL18682072 | 0.79 | ESR1 (0.40) | IDO1DAOHTR2APDE2ACYP1A2 | |
| SCHEMBL22728419 | 0.78 | ESR1 (0.43) | IDO1DAOHTR2AHTR2CPDE2A | |
| SCHEMBL12809047 | 0.78 | PPARG (0.44) | IDO1DAOPDE2AHRH4ESR1 | |
| Hydrochloric Acid SCHEMBL5178051 | 0.78 | IDO1 (0.64) | TAAR1IDO1MAOBHRH1HRH4 | |
| SCHEMBL14157121 | 0.78 | TAAR1 (0.52) | TAAR1IDO1MAOBHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914351-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | Nodthera Limited (GB) | 2021-12-01 | — | — | EP | disclosed |
| WO-2020152361-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-07-30 | — | — | WO | disclosed |