Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.84 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.84 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.51 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689256 | 1.00 | SLC6A4 (0.84) | SLC6A4SLC6A2SLC6A3SLC18A2SSTR2 | |
| SCHEMBL4615995 | 0.91 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3SLC18A2SSTR2 | |
| SCHEMBL4615998 | 0.91 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3SLC18A2SSTR2 | |
| SCHEMBL5530756 | 0.84 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC6A3SLC18A2 | |
| SCHEMBL5531939 | 0.82 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8267196 | 0.82 | SLC6A4 (0.69) | SLC6A4SLC6A2SLC6A3SLC18A2SSTR2 | |
| SCHEMBL7050745 | 0.78 | SLC6A2 (0.63) | SLC6A4SLC6A2SLC18A2SSTR2SSTR4 | |
| SCHEMBL4616122 | 0.77 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14949871 | 0.77 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC18A2SSTR2SSTR4 | |
| SCHEMBL2702774 | 0.77 | SLC6A4 (0.78) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771435-A4 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RES INST (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1771435-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | Human Biomolecular Research Institute (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006025920-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2006-03-09 | — | — | WO | disclosed |