Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.69 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530756 | 0.83 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC18A2SLC6A3MTNR1A | |
| SCHEMBL4616463 | 0.82 | SLC6A4 (0.84) | SLC6A4SLC6A2SLC18A2SLC6A3SSTR2 | |
| SCHEMBL4615998 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC18A2SLC6A3SSTR2 | |
| SCHEMBL2689256 | 0.82 | SLC6A4 (0.84) | SLC6A4SLC6A2SLC18A2SLC6A3SSTR2 | |
| SCHEMBL4615995 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC18A2SLC6A3SSTR2 | |
| SCHEMBL14949871 | 0.76 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC18A2MTNR1ANQO2 | |
| SCHEMBL7050745 | 0.75 | SLC6A2 (0.63) | SLC6A4SLC6A2SLC18A2MTNR1ANQO2 | |
| SCHEMBL576574 | 0.69 | SLC6A2 (0.57) | SLC6A4SLC6A2SLC18A2SSTR2SSTR4 | |
| SCHEMBL606293 | 0.69 | MTNR1A (0.63) | SLC6A4MTNR1ANQO2 | |
| SCHEMBL14105953 | 0.68 | SLC6A4 (0.57) | SLC6A4MTNR1ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025920-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2006-03-09 | — | — | WO | disclosed |