Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766470 | 0.75 | ATM (0.45) | TSHRALDH1A1TDP1L3MBTL1 | |
| SCHEMBL5584048 | 0.75 | CYP3A4 (0.46) | TSHRCYP3A4ALDH1A1TDP1L3MBTL1 | |
| Phthalic Acid SCHEMBL368309 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TDP1CA2HSD17B10 | |
| SCHEMBL616964 | 0.74 | ALDH1A1 (0.51) | TSHRCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL26136363 | 0.73 | CYP3A4 (0.44) | TSHRCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9058770 | 0.72 | KDM4E (0.44) | TSHRALDH1A1TDP1CA2LMNA | |
| SCHEMBL27760221 | 0.72 | ALDH1A1 (0.51) | TSHRCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL16672577 | 0.72 | HCAR2 (0.49) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL16672924 | 0.72 | MAPT (0.43) | CYP3A4ALDH1A1TDP1L3MBTL1CA2 | |
| SCHEMBL28233583 | 0.71 | TSHR (0.57) | TSHRCYP3A4ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140212490-A1 | TABLET FOR PULSED DELIVERY | SHIONOGI INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8715727-B2 | Tablet for pulsed delivery | SHIONOGI INC. (US) | 2014-05-06 | — | — | US | disclosed |
| EP-1771158-A4 | TABLET FOR PULSED DELIVERY | ADVANCIS PHARMACEUTICAL CORP (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1771158-A1 | TABLET FOR PULSED DELIVERY | Advancis Pharmaceutical Corporation (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006014427-A1 | TABLET FOR PULSED DELIVERY | ADVANCIS PHARMACEUTICAL CORPORATION (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060003005-A1 | Tablet for pulsed delivery | SHIONOGI INC. | 2006-01-05 | — | — | US | disclosed |