SCHEMBL461672

SCHEMBL461672

C=CC(c1ccccc1)C1CCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.42
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 2/20 0.37
HTR1E P28566 2/20 0.37
S1PR3 Q99500 2/20 0.37
MAPT P10636 1/20 0.37
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
HIF1A Q16665 1/20 0.35
CHRM3 P20309 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
RECQL P46063 1/20 0.34
CA1 P00915 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10784398 0.94 IDO1 (0.49) IDO1GAAL3MBTL1MEN1KMT2A
SCHEMBL1702617 0.83 SLC6A2 (0.42)
SCHEMBL2880193 0.81 SLC6A2 (0.39)
SCHEMBL29952704 0.80 IDO1 (0.42) IDO1GAAL3MBTL1MEN1KMT2A
SCHEMBL11014789 0.79 IDO1 (0.35) IDO1GAAL3MBTL1OPRD1
SCHEMBL1515769 0.76 IDO1 (0.46) IDO1GAAL3MBTL1MEN1KMT2A
SCHEMBL20336591 0.76 GAA (0.47) IDO1GAAL3MBTL1MEN1KMT2A
SCHEMBL9508994 0.76 IDO1 (0.33) IDO1OPRD1
SCHEMBL193457 0.74 IDO1 (0.49) IDO1GAAL3MBTL1MEN1KMT2A
SCHEMBL18083245 0.74 SLC6A4 (0.40) IDO1GAAL3MBTL1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552880-B2 Advanced quality control tools for manufacturing bimodal and multimodal polyethylene resins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-02-17 US disclosed
EP-3887413-B1 IMPROVED MELT FLOW INDEX RESPONSE IN POLYETHYLENE REACTORS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2024-06-12 EP disclosed
US-11969725-B2 Reactor jacket design CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-04-30 US disclosed
US-11802865-B2 Utilizing aTREF data with chemometric analysis for determining the types of polyethylene present in polymer blends and multilayer films CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-10-31 US disclosed
US-20230322973-A1 Advanced Quality Control Tools for Manufacturing Bimodal and Multimodal Polyethylene Resins CHEVRON PHILLIPS CHEMICAL COMPANY LP 2023-10-12 US disclosed
US-11708433-B2 Advanced quality control tools for manufacturing bimodal and multimodal polyethylene resins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-07-25 US disclosed
US-20230204561-A1 UTILIZING ATREF DATA WITH CHEMOMETRIC ANALYSIS FOR DETERMINING THE TYPES OF POLYETHYLENE PRESENT IN POLYMER BLENDS AND MULTILAYER FILMS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2023-06-29 US disclosed
US-11591417-B2 Deactivation methods for active components from gas phase polyolefin polymerization processes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-02-28 US disclosed
US-20230046752-A1 REACTOR JACKET DESIGN CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-02-16 US disclosed
US-11168157-B2 Melt flow index response in polyethylene reactors CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-11-09 US disclosed
WO-2011159609-A1 POLYPROPYLENE COMPOSITIONS FOR ORIENTED FILMS FINA TECHNOLOGY, INC. (US) 2011-12-22 WO disclosed
WO-2011159608-A1 POLYMERIZATION PROCESS UTILIZING HYDROGEN FINA TECHNOLOGY, INC. (US) 2011-12-22 WO disclosed
WO-2011133313-A1 FORMATION OF ZIEGLER-NATTA CATALYST USING NON-BLENDED COMPONENTS FINA TECHNOLOGY, INC. (US) 2011-10-27 WO disclosed
US-20110263802-A1 Formation of Ziegler-Natta Catalyst Using Non-blended Components FINA TECHNOLOGY, INC. (US) 2011-10-27 US disclosed
WO-2011130035-A1 BIODEGRADABLE POLYMERIC COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME FINA TECHNOLOGY, INC. (US) 2011-10-20 WO disclosed
US-20110251346-A1 Biodegradable Polymeric Compositions and Methods of Making and Using the Same FINA TECHNOLOGY, INC. (US) 2011-10-13 US disclosed
US-20110190447-A1 COMPATIBILIZED POLYPROPYLENE HETEROPHASIC COPOLYMER AND POLYLACTIC ACID BLENDS FOR INJECTION MOLDING APPLICATIONS FINA TECHNOLOGY, INC. (US) 2011-08-04 US disclosed
US-20110172379-A1 Ziegler-Natta Catalyst Systems and Polymers Formed Therefrom FINA TECHNOLOGY, INC. (US) 2011-07-14 US disclosed
WO-2011085350-A1 ZIEGLER-NATTA CATALYST SYSTEMS AND POLYMERS FORMED THEREFROM FINE TECHNOLOGY, INC. (US) 2011-07-14 WO disclosed
US-20110132519-A1 POLYOLEFIN POLYLACTIC ACID BLENDS FOR EASY OPEN PACKAGING APPLICATIONS FINA TECHNOLOGY, INC. (US) 2011-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552880-B2 Advanced quality control tools for manufacturing bimodal and multimodal polyethylene resins RAB5IF, RPS28, RPL28 IDO1 4760/4885GAA 560/4885L3MBTL1 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.