RPL28

Large ribosomal subunit protein eL28 · P46779 · RPL28 on Sugi Atlas →

3,667 patent compounds predicted against RPL28, 1,920 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL5500526	0.41	4/20
SCHEMBL5500532	0.41	4/20
SCHEMBL5503310	0.41	4/20
SCHEMBL11844361	0.35	4/20
SCHEMBL2000440	0.39	3/20
SCHEMBL8219903	0.36	3/20
SCHEMBL11627320	0.34	3/20
SCHEMBL10271044	0.55	2/20
SCHEMBL6394396	0.47	2/20
N-Methylpiperidine (SCHEMBL11205373)	0.42	2/20
Bicarbonate (SCHEMBL9058396)	0.42	2/20
SCHEMBL4960293	0.41	2/20
SCHEMBL4961968	0.40	2/20
SCHEMBL6686992	0.40	2/20
SCHEMBL9429122	0.38	2/20
Chloramphenicol (SCHEMBL10796001)	1.00	1/20
Geneticin (SCHEMBL15596)	0.93	1/20
Geneticin (SCHEMBL5006573)	0.93	1/20
Geneticin (SCHEMBL9920496)	0.93	1/20
Chloramphenicol (SCHEMBL16111)	0.90	1/20

Clinical trials — most relevant to RPL28 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes	PHASE4	UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients	PHASE2	COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension	PHASE1/PHASE2	RECRUITING
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients	PHASE1/PHASE2	COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL	PHASE1/PHASE2	RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors	PHASE1	COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors	PHASE1	COMPLETED
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery	PHASE1	COMPLETED
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates	nan	COMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease	nan	COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	nan	COMPLETED
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults	nan	COMPLETED
Exercise-induced Epigenetic Adaptations	nan	COMPLETED
RibOSE - Glucose and Resistance Exercise Training	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Lumbar Spine Muscle Degeneration Inhibits Rehabilitation-Induced Muscle Recovery	nan	COMPLETED
Selinexor (Nexpovio®) (SVd) in Patients With Relapsed or Refractory Multiple Myeloma	nan	ACTIVE_NOT_RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)	nan	COMPLETED
Na+ Channel mRNA Regulation in Heart Failure	nan	COMPLETED
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
Predictive Role of New Biomarkers for Hypersensitive Patients to Radiation in Breast Cancer (BIORISE)	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a RPL28 binder may also engage these)

Protein	Name	Similarity
P17702	—	1.000	P17702 →
G1U7L1	—	1.000	G1U7L1 →
P41105	—	0.998	P41105 →
Q3T0L7	—	0.996	Q3T0L7 →
D0VWQ3	—	0.953	D0VWQ3 →
Q95342	—	0.951	Q95342 →
Q5E973	—	0.945	Q5E973 →
P12001	—	0.944	P12001 →
Q4R5H8	—	0.942	Q4R5H8 →
RPL18	Large ribosomal subunit protein eL18	0.942	landscape →
P35980	—	0.939	P35980 →
P69090	—	0.935	P69090 →
Q58DQ3	—	0.934	Q58DQ3 →
Q2YGT9	—	0.933	Q2YGT9 →
G1TFE0	—	0.932	G1TFE0 →
P41098	—	0.931	P41098 →
Q6QMZ4	—	0.930	Q6QMZ4 →
P69091	—	0.930	P69091 →
Q9FE65	—	0.927	Q9FE65 →
P40590	—	0.927	P40590 →
Q9M352	—	0.926	Q9M352 →
Q7ZV96	—	0.925	Q7ZV96 →
G1SKF7	—	0.925	G1SKF7 →
RPL6	Large ribosomal subunit protein eL6	0.925	landscape →
Q42351	—	0.925	Q42351 →
P02412	—	0.924	P02412 →
Q90YT5	—	0.924	Q90YT5 →
P21533	—	0.924	P21533 →
Q3SX11	—	0.921	Q3SX11 →
Q90YU3	—	0.921	Q90YU3 →