Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899478 | 1.00 | GRIN2B (0.39) | GRIN2BKEAP1DRD3LMNAGID4 | |
| SCHEMBL3523506 | 0.80 | KEAP1 (0.33) | KEAP1DRD3NOS2 | |
| SCHEMBL3529213 | 0.80 | KEAP1 (0.33) | KEAP1DRD3NOS2 | |
| SCHEMBL3529215 | 0.80 | KEAP1 (0.33) | KEAP1DRD3NOS2 | |
| SCHEMBL6648853 | 0.77 | — | — | |
| SCHEMBL14916238 | 0.77 | — | — | |
| SCHEMBL14914794 | 0.77 | — | — | |
| SCHEMBL16519797 | 0.77 | GRIN2B (0.42) | GRIN2BKEAP1DRD3LMNAGID4 | |
| SCHEMBL6899248 | 0.77 | GRIN2B (0.39) | GRIN2BKEAP1DRD3LMNAGID4 | |
| SCHEMBL6101909 | 0.77 | KEAP1 (0.39) | GRIN2BKEAP1DRD3LMNAGID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881002-A1 | HCV NS-3 serine protease inhibitors | Tibotec Pharmaceuticals Ltd. (IE) | 2008-01-23 | — | — | EP | disclosed |