SCHEMBL4617602

SCHEMBL4617602

O=C1CCC(=O)C2=C(C=CCN2)N1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.36
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4184575 0.72
SCHEMBL4185142 0.65
SCHEMBL18327710 0.62
SCHEMBL26724388 0.60
SCHEMBL2815876 0.59
Succinimide SCHEMBL8361206 0.58 CRBN (1.00) CRBNKDM4E
Succinimide SCHEMBL1326078 0.58 CRBN (1.00) CRBNKDM4E
Succinimide SCHEMBL774 0.58
Succinimide SCHEMBL1466558 0.58
Succinimide SCHEMBL1600526 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879591-A1 USE OF AZAPAULLONES FOR PREVENTING AND TREATING PANCREATIC AUTOIMMUNE DISORDERS DeveloGen Aktiengesellschaft (DE) 2008-01-23 EP disclosed
WO-2006117221-A1 USE OF AZAPAULLONES FOR PREVENTING AND TREATING PANCREATIC AUTOIMMUNE DISORDERS DEVELOGEN AKTIENGESELLSCHAFT (DE) 2006-11-09 WO disclosed