Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11609607 | 0.98 | SIGMAR1 (0.47) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL13701445 | 0.98 | SIGMAR1 (0.50) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL11955738 | 0.93 | SIGMAR1 (0.46) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL11922753 | 0.86 | HRH3 (0.52) | HRH3 | |
| SCHEMBL13962700 | 0.84 | SIGMAR1 (0.54) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL12156673 | 0.84 | HRH3 (0.48) | SIGMAR1HRH3 | |
| SCHEMBL21243049 | 0.83 | SIGMAR1 (0.41) | SIGMAR1SLC6A3SLC6A4DRD2 | |
| SCHEMBL18379164 | 0.83 | SIGMAR1 (0.48) | SIGMAR1SLC6A3SLC6A4DRD2SLC6A2 | |
| SCHEMBL20333471 | 0.82 | HRH3 (0.52) | SIGMAR1SLC6A3SLC6A4HRH3 | |
| SCHEMBL10058642 | 0.82 | HRH3 (0.48) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103059005-B | Chrysin amide derivative and medical application thereof | UNIV SOUTH CENTRAL NATIONALITI | 2015-04-22 | — | — | CN | disclosed |
| CN-103059005-A | Chrysin amide derivative and medical application thereof | UNIV SOUTH CENTRAL NATIONALITI | 2013-04-24 | — | — | CN | disclosed |
| WO-2011161446-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2011-12-29 | — | — | WO | disclosed |
| US-7482352-B2 | Chemical derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2009-01-27 | — | — | US | disclosed |
| EP-1893663-B1 | METHOD FOR THE PRODUCTION OF POLYAMINES COMPRISING PRIMARY AMINO GROUPS | BAYER MATERIALSCIENCE AG (DE) | 2008-11-26 | — | — | EP | disclosed |
| EP-1893663-A1 | METHOD FOR THE PRODUCTION OF POLYAMINES COMPRISING PRIMARY AMINO GROUPS | Bayer MaterialScience AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006133839-A1 | METHOD FOR THE PRODUCTION OF POLYAMINES COMPRISING PRIMARY AMINO GROUPS | BAYER MATERIALSCIENCE AG (DE) | 2006-12-21 | — | — | WO | disclosed |
| US-20060287462-A1 | Process for preparing polyamines having primary amino groups | BAYER MATERIALSCIENCE AG (DE) | 2006-12-21 | — | — | US | disclosed |
| US-5283364-A | Hydrolysis of isocyanates with water in presence of amide solvent | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0255677-B1 | Process for producing Polyamino-hydroxy compounds containing urethane and/or urea groups and their use in the production of polyurea urethanes | BAYER AG (DE) | 1993-12-08 | — | — | EP | disclosed |
| US-4970342-A | ONE STEP HYDROLYSIS OF ISOCYANATE GROUP CONTAINING COMPOUNDS IN PRESENCE OF EXCESS WATER AND TERTIARY AMINE CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |
| US-4740531-A | REACTION INJECTION MOLDING MATERIALS; LOW VISCOSITY; COMPACT SURFACES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| EP-0255677-A1 | Process for producing Polyamino-hydroxy compounds containing urethane and/or urea groups and their use in the production of polyurea urethanes | BAYER AG (DE) | 1988-02-10 | — | — | EP | disclosed |
| EP-0219035-A2 | Process for the preparation of polyamines, and their use in the preparation of polyurethanes | BAYER AG (DE) | 1987-04-22 | — | — | EP | disclosed |
| EP-0097298-B1 | POLYAMINES, PROCESS FOR PRODUCING POLYAMINES AND THEIR USE IN THE PRODUCTION OF POLYURETHANES | BAYER AG (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0097299-B1 | POLYAMINES, PROCESS FOR PRODUCING POLYAMINES AND THEIR USE IN THE PRODUCTION OF POLYURETHANES | BAYER AG (DE) | 1986-04-16 | — | — | EP | disclosed |
| US-4501873-A | USING BASIC CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-26 | — | — | US | disclosed |
| EP-0113020-A1 | Reaction components containing amino groups, process for their preparation and their use | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0097298-A2 | Polyamines, process for producing polyamines and their use in the production of polyurethanes | BAYER AG (DE) | 1984-01-04 | — | — | EP | disclosed |
| EP-0097299-A2 | Polyamines, process for producing polyamines and their use in the production of polyurethanes | BAYER AG (DE) | 1984-01-04 | — | — | EP | disclosed |