Asperlin

Asperlin

SCHEMBL4618

CC(=O)OC1C=CC(=O)OC1C1OC1C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CA1 P00915 1/20 0.38
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 2/20 0.31
XPO1 O14980 1/20 0.31
PTPN1 P18031 2/20 0.30
TSHR P16473 1/20 0.30
NPC1 O15118 1/20 0.30
XBP1 P17861 1/20 0.30
MAPK1 P28482 1/20 0.30
AGTR1 P30556 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
MDM2 Q00987 1/20 0.30
PAX8 Q06710 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asperlin SCHEMBL8418444 1.00 CA12 (0.38) CA12CA2CA9CA1CYP3A4
Asperlin SCHEMBL34463245 1.00 CA12 (0.38) CA12CA2CA9CA1CYP3A4
Asperlin SCHEMBL8418886 1.00 CA12 (0.38) CA12CA2CA9CA1CYP3A4
SCHEMBL17350020 0.85 CA12 (0.41) CA12CA2CA9CA1CYP3A4
Cheliensisin A SCHEMBL15937020 0.82 TSHR (0.40) CYP3A4CYP2C19HSD17B10MAPTPTPN1
Cheliensisin A SCHEMBL15937093 0.82 TSHR (0.40) CYP3A4CYP2C19HSD17B10MAPTPTPN1
SCHEMBL8420179 0.75 XPO1 (0.35) CYP3A4CYP2C19HSD17B10XPO1
SCHEMBL20510650 0.73 MMP3 (0.38) CA12CA2CA9CA1CYP3A4
SCHEMBL981868 0.72 POLB (0.34) CA2CA1MAPTPTPN1NPC1
SCHEMBL21339578 0.72 POLB (0.34) CA2CA1MAPTPTPN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9633 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
EP-4524131-A1 SMALL MOLECULES FOR TREATING CANCER, INHABITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH AlonBio Ltd. (IL) 2025-03-19 EP claimed
US-12202803-B2 Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death ALONBIO LTD. (IL) 2025-01-21 US claimed
US-20240343697-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2024-10-17 US claimed
US-12109219-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2024-10-08 US claimed
WO-2024162488-A1 PHARMACEUTICAL COMPOSITION COMPRISING CUCURBITACIN D FOR PREVENTING OR TREATING NEUROPATHIC PAIN 주식회사 재인알앤피 2024-08-08 WO claimed
EP-4401780-A1 AMORPHOUS PHOTOSENSITIZING PARTICLES, METHODS FOR THE PREPARATION THEREOF, AND METHODS FOR THE USE THEREOF University of Maryland, College Park (US) 2024-07-24 EP claimed
WO-2024026505-A2 DISRUPTION OF TELOCYTE ACTIVITY PATEL AMIT (US) 2024-02-01 WO claimed
US-20240002347-A1 SMALL MOLECULES FOR TREATING CANCER, INHIBITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH ALONBIO LTD. (IL) 2024-01-04 US claimed
WO-2007059116-A2 GELDANAMYCIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF ABRAXIS BIOSCIENCE, INC. (US) 2007-05-24 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
CN-1923171-A Compound recipe anti-cancer drugs slow release agent comprising anticancer antibiotics and booster thereof JINAN KANGQUAN PHARMACEUTICAL (CN) 2007-03-07 CN claimed
CN-1923173-A Anti-cancer drugs slow release agent comprising anticancer antibiotics and booster thereof JINAN KANGQUAN PHARMACEUTICAL (CN) 2007-03-07 CN claimed
US-20060079472-A1 Methods for treating angiogenesis ANGIOSYN, INC. 2006-04-13 US claimed
CN-1634583-A Anti-cancer medicine composition containing antineoplastic antibiotics SHANDONG LANJIN BIOENGINEERING (CN) 2005-07-06 CN claimed
US-20040092583-A1 Treatment for inhibiting neoplastic lesions SHANAHAN-PRENDERGAST ELIZABETH (IE) 2004-05-13 US claimed
EP-1351678-A2 TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS Shanahan-Prendergast, Elizabeth (IE) 2003-10-15 EP claimed
EP-0687172-B1 SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF PHARMACIA AB (SE) 2002-12-04 EP claimed
WO-2002053138-A2 TREATMENT FOR INHIBITING NEOPLASTIC LESIONS USING INCENSOLE AND/OR FURANOGERMACRENS SHANAHAN-PRENDERGAST ELISABETH (IE) 2002-07-11 WO claimed