Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19215278 | 1.00 | TSHR (0.62) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL360411 | 1.00 | TSHR (0.62) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL360412 | 1.00 | TSHR (0.62) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL4620504 | 0.98 | TSHR (0.60) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL14050745 | 0.85 | CCR1 (0.68) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL17294675 | 0.84 | SOS1 (0.48) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL17294658 | 0.84 | SOS1 (0.48) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL17294673 | 0.84 | SOS1 (0.48) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL28590648 | 0.82 | RAB9A (0.58) | TSHREPHX1LMNACYP3A4CYP2C19 | |
| SCHEMBL24133917 | 0.82 | TSHR (0.61) | TSHREPHX1LMNACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888525-A1 | 3,6-DISUBSTITUTED AZABICYCLO [3.1.0]HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-02-20 | — | — | EP | claimed |
| WO-2006117754-A1 | 3,6-DISUBSTITUTED AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |