SCHEMBL461826

SCHEMBL461826

C=CCNC(=O)c1ccccc1C(N)=O.C=CCNC(=O)c1ccccc1C(N)=O.C=CCNC(=O)c1ccccc1C(N)=O.C=CCNC(=O)c1ccccc1C(N)=O

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.66
CYP1A2 P05177 2/20 0.66
MAPT P10636 2/20 0.57
ALDH1A1 P00352 6/20 0.55
TP53 P04637 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ALOX15 P16050 1/20 0.54
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
CA1 P00915 1/20 0.49
CA9 Q16790 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7870127 1.00 HPGD (0.66) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL28618627 0.98 HPGD (0.64) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL8989837 0.95 HPGD (0.60) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL5885064 0.84 HPGD (0.68) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL9087834 0.84 HPGD (0.48) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL9087828 0.84 HPGD (0.48) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL1561753 0.83 HPGD (0.66) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL14058456 0.81 HPGD (0.53) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL7978017 0.81 HPGD (0.68) HPGDCYP1A2MAPTALDH1A1TP53
SCHEMBL3459359 0.81 CA1 (0.70) HPGDCYP1A2MAPTALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906821-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-09 US claimed
EP-2445939-A2 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M Innovative Properties Company (US) 2012-05-02 EP claimed
US-20120065321-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2012-03-15 US claimed
US-7989552-B2 Improved compression set values, rheology, radiation transparency; environmentally friendly; reduced residues from organotin catalysts; phosphonium or ammonium perfluorodialkoxides, PTFE and PFA copolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-08-02 US claimed
WO-2010151610-A2 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-12-29 WO claimed
US-7666949-B2 Curing compositions for fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-02-23 US claimed
US-7592386-B2 Dual cure hydrotalcite containing fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-22 US claimed
EP-2084224-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2009-08-05 EP claimed
US-20090088517-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2009-04-02 US claimed
EP-1824918-B1 CURING COMPOSITIONS FOR FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES CO (US) 2008-12-03 EP claimed
WO-2004009660-A1 FLUOROPOLYMERS HAVING IMPROVED COMPRESSION SET 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-01-29 WO claimed
US-20040014900-A1 Fluoropolymers having improved compression set 3M INNOVATIVE PROPERTIES COMPANY 2004-01-22 US claimed
EP-1366094-A1 FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2003-12-03 EP claimed
EP-1337583-A1 FLUOROELASTOMER COMPOSITION HAVING EXCELLENT PROCESSABILITY AND LOW TEMPERATURE PROPERTIES DUPONT DOW ELASTOMERS L.L.C. (US) 2003-08-27 EP claimed
US-20020177666-A1 Fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-11-28 US claimed
US-20020145228-A1 Fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY 2002-10-10 US claimed
WO-2002060969-A1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-08-08 WO claimed
WO-2002044263-A1 FLUOROELASTOMER COMPOSITION HAVING EXCELLENT PROCESSABILITY AND LOW TEMPERATURE PROPERTIES DUPONT DOW ELASTOMERS L.L.C. (US) 2002-06-06 WO claimed
US-6326436-B2 CURABLE MIXTURE OF A COPOLYMER OF VINYLIDENE FLUORIDE, PERFLUORO(ALKYL VINYL) ETHER, 2-HYDROPENTAFLUOROPROPENE, AND OPTIONALLY TETRAFLUOROETHYLENE HAVING IODINE ATOM AT POLYMER CHAIN ENDS, POLYHYDROXY CURING AGENT AND ORGANIC PEROXIDE DUPONT DOW ELASTOMERS, L.L.C. 2001-12-04 US claimed
US-20010000343-A1 Fluoroelastomer composition having excellent processability and low temperature properties DUPONT DOW ELASTOMERS, L.L.C 2001-04-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065321-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS POLQ, QPCTL, NQO2 HPGD 2982/4885CYP1A2 1455/4885MAPT 3869/4885
US-20090088517-A1 CURING COMPOSITIONS FOR FLUOROPOLYMERS QPCTL, NQO2, POLQ HPGD 3015/4885CYP1A2 2853/4885MAPT 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.