Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9087834 | 1.00 | HPGD (0.48) | HPGDCYP1A2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL7870127 | 0.84 | HPGD (0.66) | HPGDCYP1A2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL461826 | 0.84 | HPGD (0.66) | HPGDCYP1A2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL9090113 | 0.84 | TSHR (0.41) | HPGDCYP1A2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL9090123 | 0.84 | TSHR (0.41) | HPGDCYP1A2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL8989837 | 0.83 | HPGD (0.60) | HPGDCYP1A2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL28618627 | 0.83 | HPGD (0.64) | HPGDCYP1A2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL6903284 | 0.75 | TSHR (0.58) | HPGDALDH1A1MAPTKDM4ETSHR | |
| SCHEMBL8652703 | 0.74 | TSHR (0.53) | HPGDCYP1A2ALDH1A1MAPTKDM4E | |
| SCHEMBL2129167 | 0.73 | TSHR (0.47) | HPGDALDH1A1L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |
| US-5508278-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |