Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BAX | Q07812 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408660 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| SCHEMBL4618424 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| SCHEMBL9276597 | 0.75 | MEN1 (0.39) | SMN1; SMN2CHRM5CHRM3CXCR4RAD52 | |
| SCHEMBL6921848 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| SCHEMBL710062 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| SCHEMBL208440 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| SCHEMBL28422270 | 0.73 | USP2 (0.52) | SMN1; SMN2LMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7515490 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| Ammonia Solution, Strong SCHEMBL1308109 | 0.71 | SMN1; SMN2 (0.48) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 | |
| Hydrochloric Acid SCHEMBL6619286 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2CHRM5CHRM3POLBCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893663-A1 | METHOD FOR THE PRODUCTION OF POLYAMINES COMPRISING PRIMARY AMINO GROUPS | Bayer MaterialScience AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006133839-A1 | METHOD FOR THE PRODUCTION OF POLYAMINES COMPRISING PRIMARY AMINO GROUPS | BAYER MATERIALSCIENCE AG (DE) | 2006-12-21 | — | — | WO | disclosed |
| EP-0097298-A2 | Polyamines, process for producing polyamines and their use in the production of polyurethanes | BAYER AG (DE) | 1984-01-04 | — | — | EP | disclosed |
| EP-0097299-A2 | Polyamines, process for producing polyamines and their use in the production of polyurethanes | BAYER AG (DE) | 1984-01-04 | — | — | EP | disclosed |