SCHEMBL3408660

SCHEMBL3408660

CC(CN1CCNCC1)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
CHRM5 P08912 1/20 0.39
CHRM3 P20309 1/20 0.39
POLB P06746 1/20 0.33
RAD52 P43351 1/20 0.33
CXCR4 P61073 2/20 0.32
IDO1 P14902 1/20 0.32
SIGMAR1 Q99720 3/20 0.31
PADI1 Q9ULC6 1/20 0.31
PADI4 Q9UM07 1/20 0.31
LMNA P02545 1/20 0.31
BAX Q07812 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
SLC6A2 P23975 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4618829 0.80 SMN1; SMN2 (0.42) SMN1; SMN2CHRM5CHRM3POLBRAD52
SCHEMBL25838728 0.79 MEN1 (0.42) CHRM5CHRM3SIGMAR1ALDH1A1MAPT
SCHEMBL13833229 0.77 SMN1; SMN2 (0.47) SMN1; SMN2CHRM5CHRM3POLBRAD52
SCHEMBL713548 0.77 SMN1; SMN2 (0.47) SMN1; SMN2CHRM5CHRM3POLBRAD52
SCHEMBL208440 0.77 SMN1; SMN2 (0.50) SMN1; SMN2CHRM5CHRM3POLBRAD52
SCHEMBL6921848 0.77 SMN1; SMN2 (0.50) SMN1; SMN2CHRM5CHRM3POLBRAD52
SCHEMBL28638594 0.76 GAA (0.39) SMN1; SMN2POLBALDH1A1MAPT
Hydrochloric Acid SCHEMBL6619286 0.75 SMN1; SMN2 (0.53) SMN1; SMN2CHRM5CHRM3POLBRAD52
Hydrochloric Acid SCHEMBL7515490 0.75 SMN1; SMN2 (0.53) SMN1; SMN2CHRM5CHRM3POLBRAD52
Ammonia Solution, Strong SCHEMBL1308109 0.75 SMN1; SMN2 (0.48) SMN1; SMN2CHRM5CHRM3POLBRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041665-A Preparation method of isocyanate curing agent with high trimer content 南京工业大学 2023-05-02 CN claimed
CN-109321087-A A kind of thick coated type steel structure surface high flexibility epoxy coating 厦门柏润氟材料科技有限公司 2019-02-12 CN claimed
US-12559593-B2 Dual cure sealants PRC-DESOTO INTERNATIONAL, INC. (CA) 2026-02-24 US disclosed
US-20230242710-A1 Dual Cure Sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2023-08-03 US disclosed
US-11655340-B2 Dual cure sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2023-05-23 US disclosed
CN-116041665-A Preparation method of isocyanate curing agent with high trimer content 南京工业大学 2023-05-02 CN disclosed
CN-110719928-B Dual cure sealant PRC-迪索托国际公司 2022-08-12 CN disclosed
EP-3635032-B1 DUAL CURE SEALANTS PRC DESOTO INT INC (US) 2021-08-04 EP disclosed
US-20200199300-A1 Dual Cure Sealants PRC-DESOTO INTERNATIONAL, INC. (US) 2020-06-25 US disclosed
EP-3635032-A1 DUAL CURE SEALANTS PRC-Desoto International, Inc. (US) 2020-04-15 EP disclosed
CN-110719928-A Dual cure sealant PRC-迪索托国际公司 2020-01-21 CN disclosed
CN-109321087-A A kind of thick coated type steel structure surface high flexibility epoxy coating 厦门柏润氟材料科技有限公司 2019-02-12 CN disclosed
WO-2018227149-A1 DUAL CURE SEALANTS PRC-DESOTO INTERNATIONAL, INC. (US) 2018-12-13 WO disclosed
US-20170369737-A1 URETHANE/UREA-CONTAINING BIS(ALKENYL) ETHERS, PREPOLYMERS PREPARED USING URETHANE/UREA-CONTAINING BIS(ALKENYL) ETHERS, AND USES THEREOF PRC-DESOTO INTERNATIONAL, INC. (US) 2017-12-28 US disclosed
EP-2262784-B1 INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3 SANOFI SA (FR) 2014-04-16 EP disclosed
US-8268828-B2 Inhibitors of the chemokine receptor CxCR3 SANOFI (FR) 2012-09-18 US disclosed
EP-2262784-A1 INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3 Sanofi-Aventis (FR) 2010-12-22 EP disclosed
US-20100305088-A1 INHIBITORS OF THE CHEMOKINE RECEPTOR CxCR3 SANOFI-AVENTIS (FR) 2010-12-02 US disclosed
WO-2009105435-A1 INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3 SANOFI-AVENTIS (FR) 2009-08-27 WO disclosed
US-5658660-A PREVENTS CLOUDING OF HARD DISK AND POLYGON MIRROR MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1997-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305088-A1 INHIBITORS OF THE CHEMOKINE RECEPTOR CxCR3 CXCR3, CXCR1, ACKR3 SMN1; SMN2 4238/4885CHRM5 3134/4885CHRM3 1454/4885
US-12559593-B2 Dual cure sealants DUOX2, DUOX1, GPX4 SMN1; SMN2 4670/4885CHRM5 4195/4885CHRM3 4341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.